Midnight Cowboy (1969)

An unexpected coming-of-age buddy film with two memorable characters of cinema, Ratso (Dustin Hoffman) & Joe Buck (Jon Voight), "Midnight Cowboy" collides small-town innocence with city drudgery. But is Joe Buck really innocent after having experienced the betrayal revealed in the fragmented flashbacks? Perhaps his charms and optimism seem untainted.

"Midnight Cowboy" is the street-smart version of "The Graduate" (1967). It is a testament to the dispossessed.
http://us.imdb.com/title/tt0064665/